Epidemiological study of characteristics and treatments of ameloblastoma in Japan

  • Shibahara Takahiko
    Department of Oral and Maxillo-Facial Surgery, Tokyo Dental College
  • Morita Shosuke
    First Department of Oral and Maxillofacial Surgery, Osaka Dental University
  • Sugihara Kazumasa
    Department of Maxillofacial Diagnostic and Surgical Science Field of Oral and Maxillofacial Rehabilitation Kagoshima University Graduate School of Dental and Medical Sciences
  • Minowa Kazuyuki
    Hokkaido University hospital center for advanced oral medicine
  • Yamaguchi Akira
    Section of Oral Pathology, Department of Oral Restitution, Graduate School of Tokyo Medical and Dental University
  • Yamada Takafumi
    Department of Dental Hygiene and Welfare, Meirin College
  • Nomura Takeshi
    Department of Oral and Maxillo-Facial Surgery, Tokyo Dental College

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Other Title
  • 本邦におけるエナメル上皮腫の病態と治療法に関する疫学的研究

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Abstract

We studied 947 patients with ameloblastoma who visited and were treated at the 61 institutions certified as training facilities by the Japan Society for Oral Tumors between 1995 and 2004. Ameloblastoma were reclassified according to the new WHO classification revised in 2005 and the clinicopathological data were analyzed. The patients were 581 males and 366 females. The higher age groups were 20s (18.6%) in male and 10s in female (23.2%). The most frequent and affected location was the molar region (55.6%). The frequent clinical findings were pain (46.6%) and swelling (13.6%). Radiographically, unilocular appearance was observed in 50.7 %, multilocular appearance was seen in 40.4%. Histopathologically, solid/multicystic type was observed in 74.5%, unicystic type in 17.0%, desmoplastic type in 4.1%, and extraosseous/peripheral type in 3.0%. The treatment modalities for ameloblastomas were both conservative surgery (74.0%) and radical ones (24.1%).

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