Effects of Phase III Cardiac Rehabilitation on Mortality and Cardiovascular Events in Elderly Patients With Stable Coronary Artery Disease

• Onishi Tomo

  Department of Cardiovascular Medicine, Juntendo University School of Medicine Juntendo Sports Clinic, Juntendo University Hospital

• Shimada Kazunori

  Department of Cardiovascular Medicine, Juntendo University School of Medicine Juntendo Sports Clinic, Juntendo University Hospital

• Sato Hiroyuki

  Juntendo Sports Clinic, Juntendo University Hospital Department of General Medicine, Juntendo University School of Medicine

• Seki Eriko

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Watanabe Yoshiro

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Sunayama Satoshi

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Ohmura Hirotoshi

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Masaki Yoshiyuki

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Nishitani Miho

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Fukao Kosuke

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Kume Atsumi

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Sumide Takahiro

  Juntendo Sports Clinic, Juntendo University Hospital

• Mokuno Hiroshi

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

• Naito Hisashi

  Juntendo Sports Clinic, Juntendo University Hospital Department of Sports Science, Juntendo University School of Health and Sports Science

• Kawai Sachio

  Department of Cardiovascular Medicine, Juntendo University School of Medicine Department of Sports Science, Juntendo University School of Health and Sports Science

• Daida Hiroyuki

  Department of Cardiovascular Medicine, Juntendo University School of Medicine

Abstract

Background: Cardiac rehabilitation (CR) has numerous benefits, including reduction of mortality and cardiovascular events, in patients with coronary artery disease (CAD). However, the long-term effect of phase III CR in elderly patients with stable CAD is still unknown. Methods and Results: The 111 elderly male CAD patients (≥65 years), including 37 subjects participating in supervised CR for 6 months and 74 age-matched controls, were analyzed. The patients were followed for up to 3,500 days, until the occurrence of death or 1 of the following major adverse cardiovascular events (MACE): cardiovascular death, acute coronary syndrome, refractory angina requiring revascularization, admission for congestive heart failure, or stroke. All-cause mortality tended to be lower in the CR group than in the Control group (14% vs 28%, P=0.081). The MACE incidence was significantly lower in the CR group than in the Control group (30% vs 62%, P=0.001). Multivariate Cox proportional hazard analysis showed that the MACE incidence was significantly lower in the CR group than in the Control group [adjusted hazard ratio 0.43 (95% confidence interval 0.20-0.91), P=0.027]. Conclusions: Phase III CR has the beneficial effect of reducing cardiovascular events even in elderly patients with stable CAD. (Circ J 2010; 74: 709-714)<br>

Journal

• Circulation Journal

  Circulation Journal 74 (4), 709-714, 2010

  The Japanese Circulation Society

Keywords

• Cardiovascular events
• Cardiac rehabilitation
• Coronary artery disease
• Elderly patients
• Prognosis

Details

• CRID: 1390282680078617472
• NII Article ID: 10026472427
• NII Book ID: AA11591968
• DOI: 10.1253/circj.cj-09-0638
• ISSN: 13474820
• ISSN: 13469843
• Web Site: https://www.jstage.jst.go.jp/article/circj/74/4/74_CJ-09-0638/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2010239992
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed