不妊患者における多嚢胞性卵巣症候群に対する腹腔鏡下卵巣多孔術後の治療成績

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  • Reproductive outcome after laparoscopic ovarian drilling

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Objective: The aim of this study was to evaluate the ovulatory performance and reproductive outcome after laparoscopic ovarian drilling using a harmonic scalpel in infertile women with clomiphene-resistant polycystic ovarian syndrome (PCOS).<BR>Patients: Twenty clomiphene-resistant anovulatery women with PCOS underwent laparoscopic ovarian drilling between March 2005 and December 2006.<BR>Results: After surgery, LH serum levels and the LH/FSH ratio showed statistically significant reductions, and ovulation occurred spontaneously in 70% (14/20) of the patients. The pregnancy rate was 50% (10/20) in < 1 year. Within 4 months postoperatively, 50% of all pregnancies had occurred.<BR>Conclusion: Laparoscopic ovarian drilling is an effective treatment in women with clomiphene-resistant polycystic ovarian syndrome, yet without major complications associated with medical treatment, such as ovarian hyperstimulation syndrome and, plural gestations.

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