Fractionated Stereotactic Radiotherapy as a Boost Treatment for Tumors in the Head and Neck Region
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- UNO Takashi
- Department of Radiology, Graduate School of Medicine, Chiba University
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- ISOBE Kouichi
- Department of Radiology, Graduate School of Medicine, Chiba University
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- UENO Naoyuki
- Department of Radiology, Graduate School of Medicine, Chiba University
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- FUKUDA Ataru
- Department of Neurosurgery, Fukushima Takanori Memorial Hospital
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- SUDO Satoshi
- Department of Neurosurgery, Fukushima Takanori Memorial Hospital
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- SHIROTORI Hiroaki
- Department of Neurosurgery, Fukushima Takanori Memorial Hospital
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- KITAHARA Isao
- Department of Neurosurgery, Fukushima Takanori Memorial Hospital
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- FUKUSHIMA Takanori
- Department of Neurosurgery, Fukushima Takanori Memorial Hospital
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- ITO Hisao
- Department of Radiology, Graduate School of Medicine, Chiba University
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抄録
The objective of this retrospective study was to report initial results of CyberKnife stereotactic radiotherapy (SRT) boost for tumors in the head and neck area. Between March 2008 and August 2009, 10 patients were treated with SRT boost using CyberKnife system due mainly to unfavorable condition such as tumors in close proximity to serial organs or former radiotherapy fields. Treatment sites were the external auditory canal in two, the nasopharynx in one, the oropharynx in three, the nasal cavity in one, the maxillary sinus in two, and the oligometastatic cervical lymph node in one. All patients underwent preceding conventional radiotherapy of 40 to 60 Gy. Dose and fractionation scheme of the Cyberknife SRT boost was individualized, and prescribed dose ranged from 9 Gy to 16 Gy in 3 to 4 fractions. Among four patients for whom dose to the optic pathway was concerned, the maximum dose was only about 3 Gy for three patients whereas 9.6 Gy in the remaining one patient. The maximum dose for the mandible in one of three patients with oropharyngeal cancer was 19.7 Gy, whereas majority of the bone can be spared by using non-isocentric conformal beams. For a patient with nasopharyngeal cancer, the highest dose in the brain stem was 15 Gy. However, majority of the brain stem received less than 40% of the maximum dose. Although a small volume high dose area within the normal structure could be observed in several patients, results of the present study showed potential benefits of the CyberKnife SRT boost.
収録刊行物
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- Journal of Radiation Research
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Journal of Radiation Research 51 (4), 449-454, 2010
Journal of Radiation Research 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390282680192300800
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- NII論文ID
- 10026564008
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- NII書誌ID
- AA00705792
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- COI
- 1:STN:280:DC%2BC3cjhvVyjuw%3D%3D
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- ISSN
- 13499157
- 04493060
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- NDL書誌ID
- 10766115
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- PubMed
- 20508374
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可