Characteristics of Complex Fractionated Atrial Electrogram in the Electroanatomically Remodeled Left Atrium of Patients With Atrial Fibrillation
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- Park Jae Hyung
- Yonsei University Health System
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- Park Sang Weon
- Korea University College of Medicine
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- Kim Jong Youn
- Yonsei University Health System
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- Kim Sook Kyoung
- Yonsei University Health System
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- Jeoung Boyoung
- Yonsei University Health System
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- Lee Moon-Hyung
- Yonsei University Health System
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- Hwang Chun
- Krannert Heart Institute , Indianapolis University
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- Kim Young-Hoon
- Korea University College of Medicine
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- Kim Sung Soon
- Yonsei University Health System
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- Pak Hui-Nam
- Yonsei University Health System
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Background: Complex fractionated atrial electrogram (CFAE) guided ablation is effective in some patients with persistent atrial fibrillation (PeAF), but the pattern of CFAE may be different in the remodeled left atrium (LA). Methods and Results: In 100 AF patients (83 males, 55.0±10.6 years old) with AF (51 paroxysmal AF (PAF), 49 PeAF) who underwent catheter ablation, CFAE cycle length (CL) and distribution (NavX 3D map) were compared according to the LA volume (3D-CT) and endocardial voltage (during high right atrial pacing 500-ms (VolPACE) and AF (VolAF; NavX). The mean CFAE-CL was longer (P=0.003) and the % area CFAE was smaller (P=0.006) in patients with LA ≥125 ml than those with <125 ml. The mean CFAE-CL was longer in patients with VolPACE <1.7 mV than those with ≥1.7 mV (P=0.002) and in VolAF <0.7 mV than ≥0.7 mV (P<0.001). The % area CFAE was smaller in patients with VolPACE <1.7 mV than those with ≥1.7 mV (P=0.006). The incidence of septal CFAE was consistently high, regardless of the degree of LA remodeling. Conclusions: In the AF patients with an electroanatomically remodeled LA, the % area of CFAE was smaller and mean CFAE-CL was longer than in those with a less remodeled LA. However, the majority of CFAE are consistently positioned on the septum in the remodeled LA. (Circ J 2010; 74: 1557 - 1563)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 74 (8), 1557-1563, 2010
一般社団法人 日本循環器学会
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詳細情報
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- CRID
- 1390001205104463744
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- NII論文ID
- 10026565452
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可