Cellular Localization of Nerve Growth Factor (NGF) and Its Receptors TrkA and p75LNGFR in the Ovary of the Japanese Monkey (Macaca fuscata fuscata).

• SHIMIZU Keiko

  Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto University

• JIN WanZhu

  Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University

• KOJIMA Chihiro

  Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology

• SHI ZhanQuan

  Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University

• KONDO Masahiro

  Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University

• ITOH Mariko

  Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto University

• WATANABE Gen

  Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University

• TAYA Kazuyoshi

  Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology Department of Basic Veterinary Sciences, The United Graduate School of Veterinary Sciences, Gifu University

抄録

Cellular localization of nerve growth factor (NGF) and its receptors (TrkA, p75LNGFR) in the ovary of the Japanese monkey (Macaca fuscata fuscata) was investigated using immunohistochemistry. Strong positive immunostaining for NGF was confined to granulosa and theca cells of large antral follicles in the ovary. The interstitial cells also showed positive immunostaining for NGF. The intensity of immunostaining for TrkA was stronger in granulosa and interstitial cells than in theca cells. Immunoreactions for p75LNGFR were detectable in granulosa, interstitial and theca cells of the ovary. These results strongly suggest autocrine and paracrine regulation of follicular function by NGF in the ovary of the Japanese monkey.<br>

収録刊行物

• Journal of Reproduction and Development

  Journal of Reproduction and Development 48 (4), 377-381, 2002

  公益社団法人 日本繁殖生物学会

キーワード

• NGF
• TrkA
• p75LNGFR
• Ovary
• Japanese monkey

詳細情報

• CRID: 1390001206336452864
• NII論文ID: 10026617246
• NII論文ID: 130000054950
• NII書誌ID: AA10936678
• DOI: 10.1262/jrd.48.377
• COI: 1:CAS:528:DC%2BD38XntFyqsrk%3D
• ISSN: 13484400
• ISSN: 09168818
• NDL書誌ID: 6272056
• Web Site: http://id.ndl.go.jp/bib/6272056
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I6272056
• Web Site: http://www.jstage.jst.go.jp/article/jrd/48/4/48_4_377/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2003054443
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
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  • KAKEN
• 抄録ライセンスフラグ: 使用不可