妊婦に生じた Zosteriform Angiolymphoid Hyperplasia with Eosinophilia の1例  [in Japanese] A Case of Zosteriform Angiolymphoid Hyperplasia with Eosinophilia in Pregnancy  [in Japanese]

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Abstract

22歳,女性。妊娠32週0経妊0経産。妊娠14週頃から下顎部にそう痒を伴う丘疹が出現し,前頚部に拡大した。片側性に帯状に集簇していたため,近医内科で帯状疱疹と診断され,抗ウイルス剤を外用したが無効であった。その後全身に漿液性丘疹が出現,多形紅斑様となり,プレドニゾロン 15 mg/日内服して軽快するも前頚部の皮疹が難治のため当科を紹介受診した。下顎部右側から前頚部右側に径数mmまでの紅色丘疹が集簇,融合して局面を形成し,全体として帯状疱疹様に分布していた。生検の結果angiolymphoid hyperplasia with eosinophiliaと診断し,プレドニゾロンを減量し,経過観察した。正常分娩後に局面は急速に縮小,瘢痕様となり,プレドニゾロンは分娩後5ヵ月で中止したが,丘疹,多形紅斑の再燃もない。

A 22-year-old woman experienced red papules and pruritus on her right submandibular and right anterior neck region during the second trimester of her pregnancy. A diagnosis of herpes zoster was made and topical acyclovir ointment was adminstered with no clinical improvement. Several weeks later, red papules developed on her trunk and extremities, and became erythema multiforme-like in appearance. Although the generalized papules subsided after administration of oral prednisolone 15 mg/day, the neck lesions were intractable. She was then referred to our hospital. Physical examination revealed red papules and plaques grouped on her right submandibular and right anterior neck region in a zosteriform distribution. Histopathological examination of a papule revealed patchy infiltration of lymphocytes and eosinophils throughout the dermis. The endothelial cells of the capillaries were prominent and swollen. A diagnosis of angiolymphoid hyperplasia with eosinophilia was made. Oral prednisolone was tapered but continued. The papules and plaques subsided gradually after she delivered a normal healthy boy.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 72(4), 356-358, 2010-08-01

    Western Division of Japanese Dermatological Association

References:  11

Codes

  • NII Article ID (NAID)
    10026636878
  • NII NACSIS-CAT ID (NCID)
    AN00183881
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    03869784
  • NDL Article ID
    10806412
  • NDL Source Classification
    ZS39(科学技術--医学--皮膚科学・泌尿器科学)
  • NDL Call No.
    Z19-69
  • Data Source
    CJP  NDL  J-STAGE 
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