Cutting–Edge of Membrane Stress Biotechnology

• Kuboi Ryoichi

  Dept. of Chem. Sci. & Eng. Graduate School of Eng. Sci. Osaka University

• Umakoshi Hiroshi

  Dept. of Chem. Sci. & Eng. Graduate School of Eng. Sci. Osaka University

• Shimanouchi Toshinori

  Dept. of Chem. Sci. & Eng. Graduate School of Eng. Sci. Osaka University

Bibliographic Information

Other Title

• メンブレン・ストレスバイオテクノロジーの新展開
• メンブレン ストレス バイオテクノロジー ノ シンテンカイ

Abstract

A “Biomembrane”is a key interface to integrate production and separation of target materials through the creationof “new order”on its surface. A model biomembrane, liposome, can recognize (separate)the (bio)moleculesthrough (i)electrostatic, (ii)hydrophobic interaction, and (iii)stabilization effect of hydrogen bonds in the hydropho-bic lipid environment. A novel biomembrane-based catalysis (LIPOzyme: liposome + enzyme)can be designed anddeveloped by integrating the above recognition sites and a simple catalytic center on the liposome surface. A processdesign utilizing LIPOzyme chemistry and the recognition (bioseparation)functions of model-biomembrane (lipo-some)is the basic strategy to achieve a “Biomembrane Process Chemistry”as an application of “Membranomics”.

Journal

• MEMBRANE

  MEMBRANE 33 (6), 300-306, 2008

  THE MEMBRANE SOCIETY OF JAPAN

Keywords

• membranome
• liposome
• LIPOzyme
• membrane chip
• Alzheimer's disease

Details

• CRID: 1390001206423360512
• NII Article ID: 10026876763
• NII Book ID: AN0023215X
• DOI: 10.5360/membrane.33.300
• ISSN: 18846440
• ISSN: 03851036
• ISSN: http://id.crossref.org/issn/03851036
• NDL BIB ID: 9739333
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9739333
• Web Site: https://www.jstage.jst.go.jp/article/membrane/33/6/33_300/_pdf
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed