Membranomics Research on Interactions between Liposome Membranes with Membrane Chip Analysis

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Author(s)

Abstract

The liposome immobilized on indium tin–oxide (ITO) electrode was prepared to evaluate the liposome–liposome interaction to develop "Membrane Chip". Three kinds of standard liposomes entrapping the fluorescence probe, calcein, were used for their immobilization, where the immobilized liposomes show the different characteristics in their phase transition temperature and membrane fluidity. Membrane Chip could give the set of the quantitative information relating to the membrane–membrane interaction. The interaction between three immobilized liposomes and 22 kinds of liposomes as samples was then systematically investigated on a basis of the calcein release from the immobilized liposomes, which could give the information in relation to "Membranome". It was, therefore, found that the Membrane Chip as a means of Membranomics research was effective to evaluate the Membranome information of liposomes.

Journal

  • MEMBRANE

    MEMBRANE 34(6), 342-350, 2009-11-01

    THE MEMBRANE SOCIETY OF JAPAN

References:  32

Codes

  • NII Article ID (NAID)
    10026876933
  • NII NACSIS-CAT ID (NCID)
    AN0023215X
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    03851036
  • NDL Article ID
    10505182
  • NDL Source Classification
    ZR2(科学技術--生物学--生化学)
  • NDL Call No.
    Z18-1127
  • Data Source
    CJP  NDL  J-STAGE 
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