Membranomics Research on Interactions between Liposome Membranes with Membrane Chip Analysis

DOI Web Site Web Site 3 Citations 32 References
  • Shimanouchi Toshinori
    Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
  • Oyama Ena
    Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
  • Umakoshi Hiroshi
    Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University
  • Kuboi Ryoichi
    Division of Chemical Engineering, Graduate School of Engineering Science, Osaka University

Search this article

Abstract

The liposome immobilized on indium tin–oxide (ITO) electrode was prepared to evaluate the liposome–liposome interaction to develop “Membrane Chip”. Three kinds of standard liposomes entrapping the fluorescence probe, calcein, were used for their immobilization, where the immobilized liposomes show the different characteristics in their phase transition temperature and membrane fluidity. Membrane Chip could give the set of the quantitative information relating to the membrane–membrane interaction. The interaction between three immobilized liposomes and 22 kinds of liposomes as samples was then systematically investigated on a basis of the calcein release from the immobilized liposomes, which could give the information in relation to “Membranome”. It was, therefore, found that the Membrane Chip as a means of Membranomics research was effective to evaluate the Membranome information of liposomes.

Journal

  • MEMBRANE

    MEMBRANE 34 (6), 342-350, 2009

    THE MEMBRANE SOCIETY OF JAPAN

Citations (3)*help

See more

References(32)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top