心筋梗塞における前回梗塞から再梗塞までの期間に関連する要因の検討

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  • Factors related to the time between myocardial infarction and its recurrence.

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This study focuses on cases of recurrent myocardial infarction, and the time between a previous occurrence and recurrence to develop measures to elucidate factors related to the length of this interval prevent recurrence. Subjects were 78 male patients hospitalized at Showa University Hospital, who met the criteria of having records of the time from a previous myocardial infarction until a recurrence. The average interval from a prior myocardial infarction until a recurrence was 67.0 months. Items surveyed included : sex, date of birth, date of previous myocardial infarction, date of recurrence, employed/ unemployed, total serum cholesterol level, serum neutral lipid level, obesity level, presence or absence of hypertension, presence or absence of diabetes, smoker/nonsmoker, presence of absence of hyperuricemia. and family history if any. CATDAP-02 was used to analyze possible relations between the occurrence-recurrence interval and the items surveyed. The results indicated statistical significance of the relation of total serum cholesterol and obesity levels with the time from the occurrence of a myocardial infarction to recurrence. A + 10% to + 15% obesity level had a significant relationship especially for +13% which had a maximum level of significance, whereas + 20% (the usual conventional standard) was only weakly related to the time betweem occurrence and recurrence. A total serum cholesterol level of 180mg/dl to 200mg/dl was related, and this relation was stronger at 180mg/dl, in partcular. No relation was evident at 220mg/dl, which has been conventionally used as a criterion. These findings suggest a need to maintain lower than usually indicated levels of obesity and total serum cholesterol after a myocardial infarction experience.

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