疼痛に関与する伝導路と下行性疼痛抑制系  [in Japanese] Pain Pathways and Descending Inhibitory Pathways Implicated in Nociceptive Modulation  [in Japanese]

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Author(s)

    • 大島 秀規 OSHIMA Hideki
    • 日本大学医学部機能形態学系生体構造医学分野 Department of Functional Morphology, Nihon University School of Medicine

Abstract

The ascending pain pathway consists of many complex neural structures, including specialized nociceptive receptors and peripheral nociceptive neurons in the dorsal root ganglion, spinal dorsal horn nociceptive and wide-dynamic range neurons, that play a role in the initial central neural processing for nociceptive information, several divergent relay stations (the thalamic nuclei and several nuclei in the brainstem) that properly mediate a variety of reflex reactions to painful stimuli, and are variously distributed among the thalamo-cortical and limbic circuits for sensory perception, learning, memory and other cognitive activity, and emotional responses. In addition to the ascending pain pathway, there are descending pathways that modulate pain by inhibiting nociceptive transmission. The purpose of the present review is to summarize the current knowledge of the structure of the pain system, including both the ascending and the descending components.

Journal

  • Journal of Nihon University Medical Association

    Journal of Nihon University Medical Association 69(3), 159-163, 2010-06-01

    NIHON UNIVERSITY MEDICAL ASSOCIATION

References:  17

Codes

  • NII Article ID (NAID)
    10026989004
  • NII NACSIS-CAT ID (NCID)
    AN0018408X
  • Text Lang
    JPN
  • Article Type
    REV
  • Journal Type
    大学紀要
  • ISSN
    00290424
  • NDL Article ID
    10767461
  • NDL Source Classification
    ZS7(科学技術--医学)
  • NDL Call No.
    Z19-263
  • Data Source
    CJP  NDL  J-STAGE 
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