Aortic Annular Velocity Assessed by Tissue Doppler Echocardiography as a Potential Parameter of Arterial Stiffness

DOI Web Site 被引用文献3件 参考文献30件
  • Masugata Hisashi
    Department of Integrated Medicine, Kagawa University
  • Senda Shoichi
    Department of Integrated Medicine, Kagawa University
  • Okuyama Hiroyuki
    Department of Integrated Medicine, Kagawa University
  • Murao Koji
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University
  • Hosomi Naohisa
    Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences
  • Inukai Michio
    Department of Integrated Medicine, Kagawa University
  • Iwado Yasuyoshi
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University
  • Noma Takahisa
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University
  • Kohno Masakazu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Kagawa University
  • Goda Fuminori
    Department of Integrated Medicine, Kagawa University

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Although mitral annular velocity assessed by tissue Doppler echocardiography has been established as a parameter of left ventricular (LV) diastolic function, aortic annular velocity has never been investigated as a parameter of cardiovascular function. We investigated whether aortic annular velocity can be measured using the same tissue Doppler echocardiographic method that is used for measuring mitral annular velocity, as well as the correlation between the aortic annular velocity thus measured and arterial stiffness that was assessed by the cardio-ankle vascular index (CAVI). Sixty-three patients (69 ± 13 years) with hypertension, diabetes, or dyslipidemia, who had no overt heart disease, were enrolled. The mitral and aortic annular velocities were measured at the mitral and aortic annuluses, respectively, using tissue Doppler echocardiography. Aortic annular velocity was successfully obtained in all patients. The correlation between the peak early diastolic aortic annular velocity (r = −0.803, p < 0.001) and CAVI as an index of arterial stiffness was greater than that of the peak early diastolic mitral velocity and CAVI (r = −0.649, p < 0.001). Stepwise regression analysis showed that the age (β coefficient = 0.488, p = 0.002) and the peak early diastolic aortic annular velocity (β coefficient = −0.405, p = 0.008) were independent determinants of the CAVI. The strong inter-relationship was found between left ventricular diastolic function assessed by the aortic annular velocity and arterial stiffness assessed by CAVI. In conclusion, the aortic annular velocity may be helpful for assessing arterial stiffness in patients with cardiovascular risk factors.

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