Bisphenol-A contents in materials used in pediatric dentistry

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Author(s)

    • KANEKO Shoko
    • Department of Pediatric Dentistry, Showa University, School of Dentistry
    • MANABE Atsufumi
    • Department of Operative Dentistry, Showa University, School of Dentistry
    • NUMAZAWA Satoshi
    • Department of Biochemical Toxicology, Showa University, School of Pharmaceutical Sciences
    • ITOH Kazuo
    • Department of Operative Dentistry, Showa University, School of Dentistry
    • INOUE Mitsuko
    • Department of Pediatric Dentistry, Showa University, School of Dentistry
    • YOSHIDA Takemi
    • Department of Biochemical Toxicology, Showa University, School of Pharmaceutical Sciences
    • SASA Ryuji
    • Department of Pediatric Dentistry, Showa University, School of Dentistry

Abstract

Bisphenol-A (BPA) has been shown to be an endocrine disruptor in animals. We have previously demonstrated selective extraction of BPA from dental materials and its detection by gas chromatography-mass spectrometry. In the present study, this same procedure was employed for the detection of BPA in materials routinely used in pediatric dentistry—commercial resin composites, fissure sealants, compomers, and dentin bonding agents. In unpolymerized materials, significant BPA contamination was detected in 2 of 3 resin composites, 2 of 5 fissure sealants, and all bonding agents and intermediate resins tested. Moreover, in most cases, incubation of polymerized materials for 24 h resulted in release of BPA into phosphate-buffered saline. However, the highest level of BPA released (89.5 ng/g polymerized material) was still far less than the reported lowest dose that produces endocrine disruption in experimental animals (2μg/kg/d).

Journal

  • Pediatric Dental Journal

    Pediatric Dental Journal 14(1), 17-21, 2004-03-20

    The Japanese Society of Pediatric Dentistry

References:  19

Codes

  • NII Article ID (NAID)
    10027096550
  • NII NACSIS-CAT ID (NCID)
    AA10809637
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    09172394
  • Data Source
    CJP  J-STAGE 
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