Tsukuba-green : A Fluorescent Dye that Emits Green Fluorescence Useful for Live-cell Imaging

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Author(s)

    • SENDA Naoko
    • Graduate School of Pure and Applied Sciences, University of Tsukuba
    • MIWA Yoshihiro
    • Department of Molecular Pharmacology, Institue of Basic Medical Sciences, University of Tsukuba
    • TANAKA Junko
    • Center for Tsukuba Advanced Research Alliance, University of Tsukuba
    • MOMOTAKE Atsuya
    • Graduate School of Pure and Applied Sciences, University of Tsukuba
    • ARAI Tatsuo
    • Graduate School of Pure and Applied Sciences, University of Tsukuba

Abstract

A new fluorescent dye, 4-ethoxycarbonylmethyl-2-methyl-7-hydroxyquinoline (TG) was obtained unexpectedly from the BiCl<sub>3</sub>-catalyzed Pechmann condensation. TG emits green fluorescence at 509 nm in water. For live-cell imaging applications, TG derivatives TG1–TG3 were prepared. Under physiological conditions, HEp-2 cells were immediately stained upon addition of a solution of TG3.

Journal

  • Chemistry Letters

    Chemistry Letters 39(3), 308-310, 2010-03-05

    The Chemical Society of Japan

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Codes

  • NII Article ID (NAID)
    10027178817
  • NII NACSIS-CAT ID (NCID)
    AA00603318
  • Text Lang
    ENG
  • Article Type
    SHO
  • ISSN
    03667022
  • Data Source
    CJP  J-STAGE 
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