Improvement in Symptoms and QuantiFERON TB-2G Test Results after Isoniazid Administration in a Patient with Normal Routine Tests Results

• Kawada Etsuo

  Ninosawa Hospital

• Sato Hiroko

  Department of General Medicine, Gunma University Hospital

• Kaneko Naoko

  Department of General Medicine, Gunma University Hospital

• Ohyama Yoshio

  Department of General Medicine, Gunma University Hospital

• Tamura Jun'ichi

  Department of General Medicine, Gunma University Hospital

Abstract

Diagnosis is difficult in patients who complain of slight fever without objective abnormalities. It is not rare that patients without signs of typical Mycobacterium tuberculosis (TB) infection have a delayed TB diagnosis. It has been reported that the QuantiFERON TB-2G test is useful for diagnosing latent TB infection. We report a patient who suffered from sweating, body weight loss, and a fever of less than 37.5C without abnormalities in routine tests. Except for his complaints, only QuantiFERON TB-2G testing suggested his illness, after which he was successfully treated with isoniazid administration. QuantiFERON TB-2G testing might be useful to diagnose patients with slight fever when TB is suspected but a conventional workup is not diagnostic.

Journal

• General Medicine

  General Medicine 11 (1), 31-34, 2010

  Japan Primary Care Association

Keywords

• tuberculosis
• QuantiFERON TB
• inflammatory biomarkers
• slight fever

Details

• CRID: 1390282680164856704
• NII Article ID: 10027253292
• NII Book ID: AA11571086
• DOI: 10.14442/general.11.31
• ISSN: 18836011
• ISSN: 13460072
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed