Influence of Dynamic Training on Hemodynamic, Neurohormonal Responses to Static Exercise and on Inflammatory Markers in Patients After Coronary Artery Bypass Grafting

DOI Web Site 被引用文献7件 参考文献25件
  • Bilinska Maria
    Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, Institute of Cardiology
  • Kosydar-Piechna Magdalena
    Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, Institute of Cardiology
  • Gasiorowska Anna
    Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences
  • Mikulski Tomasz
    Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences
  • Piotrowski Walerian
    Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Cardiology
  • Nazar Krystyna
    Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences
  • Piotrowicz Ryszard
    Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, Institute of Cardiology

この論文をさがす

抄録

Background:  Little is known about the influence of dynamic training on the hemodynamic and neurohormonal responses to static exercise and on inflammatory markers in optimally treated post-coronary artery bypass grafting (CABG) patients. Methods and Results:  One hundred and twenty male patients, aged 55±6 years, 3 months after receiving CABG, were randomized to either 6 weeks of aerobic training on a cycloergometer, 3 times a week, at a 70-80% of the maximum tolerated heart rate (HR) (training group, n=60) or to a control group (n=60). At baseline and at the end of the study, all patients underwent: (1) a cardiopulmonary test; (2) handgrip at 30% of maximal voluntary contraction for 3min in a sitting position during in which HR, blood pressure (BP), stroke volume (SV, by impedance cardiography), cardiac output (CO) and total peripheral resistance (TPR) were monitored; and (3) plasma level assessment of catecholamines, nitric oxide and inflammatory markers. During the final tests, handgrip-induced increases in HR, BP, and TPR (14% vs 27%, P<0.01) were lower, whereas SV and CO were higher (by 13% and 15%, respectively, P<0.05) in trained patients compared with controls. Moreover, a higher increase in nitric oxide level (46% vs 14%, P<0.01) and a lower increase in noradrenaline (11% vs 20%, P<0.05) were observed in trained patients compared with controls. Accordingly, training caused significant improvement in peak oxygen uptake per kilogram body weight (peak VO2) and inflammatory markers. Conclusions:  Short-term dynamic training caused significant improvement of hemodynamic and neurohormonal responses to handgrip, cardiovascular fitness and inflammatory state. (Circ J 2010; 74: 2598-2604)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 74 (12), 2598-2604, 2010

    一般社団法人 日本循環器学会

被引用文献 (7)*注記

もっと見る

参考文献 (25)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ