Combined Assessment of Myocardial Perfusion and Function by ECG-Gated Myocardial Perfusion Single-Photon Emission Computed Tomography for the Prediction of Future Cardiac Events in Patients With Type 2 Diabetes Mellitus

DOI Web Site 被引用文献5件 参考文献48件
  • Kato Masahiko
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
  • Matsumoto Naoya
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
  • Nakano Yoshimochi
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
  • Suzuki Yasuyuki
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
  • Yoda Shunichi
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
  • Sato Yuichi
    Department of Imaging, Health Park Clinic
  • Kasama Shu
    Department of Cardiovascular Medicine, Gunma University School of Medicine
  • Nagao Ken
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine
  • Hirayama Atsushi
    Division of Cardiology, Department of Medicine, Nihon University School of Medicine

この論文をさがす

抄録

Background: The mid-term prognostic significance of ECG-gated single-photon emission computed tomography (SPECT) remains unclear in Japanese patients with type 2 diabetes mellitus (DM). In the present study rates of future cardiac events (nonfatal acute myocardial infarction (AMI), cardiac death (CD) and severe heart failure (HF) requiring hospitalization) were compared in patients with and without DM. Methods and Results: 1,810 patients (563 DM and 1,247 non-DM) we followed for a mean of 26.3±15.5 months. Summed stress score (SSS), summed difference score (SDS), poststress ejection fraction (EF) and resting end-diastolic volume (EDV) were calculated. In total, 20 cases of AMI (9 in DM (1.59%) and 11 in non-DM (0.88%)), 20 of CD (7 in DM patients (1.24%) and 13 in non-DM (1.04%)) and 54 of severe HF (31 in DM (5.5%) and 23 in non-DM (1.84%)) occurred. Univariate Cox analysis showed that, in DM patients, predictors of total cardiac events were poststress EF (Wald 60.4; P<0.001), resting EDV (Wald 53.8; P<0.001), SSS (Wald 39.6; P<0.001), SDS (Wald 26.1; P<0.001), history of prior MI (Wald 4.32; P<0.05) and hemoglobin A1c value (Wald 4.30; P<0.05). Multivariate Cox analysis showed that poststress EF (Wald 9.85; P<0.01) and SDS (Wald 6.19; P<0.01) were independent predictors of total cardiac events. Conclusions: Combined assessment of perfusion and function by ECG-gated SPECT may predict future cardiac events in type 2 DM patients. (Circ J 2011; 75: 376-382)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 75 (2), 376-382, 2011

    一般社団法人 日本循環器学会

被引用文献 (5)*注記

もっと見る

参考文献 (48)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ