コサンケイにおける腸管原発粘液性腺癌  [in Japanese] Primary Intestinal Mucinous Adenocarcinoma in an Edward's Pheasant  [in Japanese]

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Abstract

動物園で飼育されていた10歳,雄,コサンケイ(<i>Lophura edwardsi</i>)が死亡した. 剖検時,回腸下部から大腸上部に乳白色卵円形腫瘤(4.5×4×4cm)が認められた. 腫瘍組織はおもに腸管粘膜固有層にみられ,多量の粘液中に弧在性または集塊状に認められた. これらは薄い結合組織により取り囲まれ,蜂窩状の粘液結節を形成していた. この粘液はアルシアンブルー染色(pH1.0,pH2.5),トルイジンブルー染色,過ヨウ素酸シッフ(PAS)反応およびムチカルミン染色陽性であり,上皮性の酸性粘液と考えられた. 免疫組織化学的に腫瘍細胞は上皮の特性を示し,トリ白血病ウイルス抗原陰性であった. 粘液中に浮遊した腫瘍細胞塊の細胞間にはデスモゾームがみられた. 以上から,本例は鳥類で初めて報告される腸管原発の粘液性腺癌の症例と考えられた.

A ten-year-old male Edward's pheasant (<i>Lophura edwardsi</i>) was found dead in a zoo. At necropsy, an oval-shaped mass (4.5× 4 × 4cm) was located in the digestive tract, involving the lower small intestine and the upper large intestine. The mass was creamy white in color. Histologically, the neoplastic tissues were detected mainly in the lamina propria of the affected intestine. Single or clumps of tumor cells were detected in substantial amounts of mucus, forming mucous lakes. Most of the mucous lakes were surrounded by thin connective tissues. As the mucus was positively stained with Alcian blue (pH1.0, pH2.5), toluidine blue, periodic acid Schiff (PAS) and Mucicarmine, the mucus was considered to be acid mucin of epithelial origin. Ultrastructurally, the plasma membranes of the tumor cells were connected with desmosomes. The case was diagnosed as intestinal mucinous adenocarcinoma. It is the first report of an intestinal mucinous adenocarcinoma in a bird.

Journal

  • Journal of the Japan Veterinary Medical Association

    Journal of the Japan Veterinary Medical Association 63(12), 935-938, 2010-12-20

    Japan Veterinary Medical Association

References:  22

Codes

  • NII Article ID (NAID)
    10027476709
  • NII NACSIS-CAT ID (NCID)
    AN00191857
  • Text Lang
    JPN
  • Article Type
    SHO
  • ISSN
    04466454
  • NDL Article ID
    10947967
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-352
  • Data Source
    CJP  NDL  IR  J-STAGE 
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