Effects of Various Amino Acids on Methionine-Induced Hyperhomocysteinemia in Rats

• FUKADA Shin-ichiro

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

• MORITA Tatsuya

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

• SUGIYAMA Kimio

  Department of Applied Biological Chemistry, Faculty of Agriculture, Shizuoka University

Abstract

Rats were fed diets supplemented with 1% L-methionine with and without 2.5% various amino acids for 7 d to determine what amino acids other than glycine, serine, and cystine can suppress methionine-induced hyperhomocysteinemia. L-Glutamic acid, L-histidine, and L-arginine significantly suppressed methionine-induced enhancement of plasma homocysteine concentrations, but the mechanisms underlying the effect of these amino acids are thought not to be identical.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 72 (7), 1940-1943, 2008

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• homocysteine
• methionine
• glutamic acid
• histidine
• arginine

Details

• CRID: 1390001206480528000
• NII Article ID: 10027530402
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.70833
• ISSN: 13476947
• ISSN: 09168451
• NDL BIB ID: 9596653
• Web Site: http://hdl.handle.net/10297/2609
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9596653
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.70833
• Web Site: https://search.jamas.or.jp/link/ui/2009046084
• Text Lang: en
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed