Regioselectivity of Larock Indole Synthesis Using Functionalized Alkynes

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Author(s)

Abstract

Regioselectivity of Larock indole synthesis, a palladium-catalyzed heteroannulation between <I>o</I>-iodoaniline and internal acetylene, was estimated using acetylenes substituted with ester and/or Boc-protected amine at the homopropargylic position and with perbenzyl- and unprotected glucose. Low to moderate regioselectivities were observed in all the cases, indicating these functional groups do not exert good directing effects, in the Larock indole synthesis.

Journal

  • Bioscience, Biotechnology, and Biochemistry

    Bioscience, Biotechnology, and Biochemistry 72(8), 2092-2102, 2008-08-23

    Japan Society for Bioscience, Biotechnology, and Agrochemistry

References:  23

Codes

  • NII Article ID (NAID)
    10027530880
  • NII NACSIS-CAT ID (NCID)
    AA10824164
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    09168451
  • NDL Article ID
    9627923
  • NDL Source Classification
    ZR7(科学技術--農林水産--農産) // ZR2(科学技術--生物学--生化学) // ZP1(科学技術--化学・化学工業)
  • NDL Call No.
    Z53-G223
  • Data Source
    CJP  NDL  J-STAGE 
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