Disruption of the SCS2 Ortholog in the Alkane-Assimilating Yeast Yarrowia lipolytica Impairs Its Growth on n-Decane, but Does Not Impair Inositol Prototrophy
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- Kobayashi Satoshi KOBAYASHI Satoshi
- Department of Biotechnology, The University of Tokyo
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- Hirakawa Kiyoshi HIRAKAWA Kiyoshi
- Department of Biotechnology, The University of Tokyo
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- Fukuda Ryouichi [他] FUKUDA Ryouichi
- Department of Biotechnology, The University of Tokyo
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- OHTA Akinori
- Department of Biotechnology, The University of Tokyo
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Author(s)
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- Kobayashi Satoshi KOBAYASHI Satoshi
- Department of Biotechnology, The University of Tokyo
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- Hirakawa Kiyoshi HIRAKAWA Kiyoshi
- Department of Biotechnology, The University of Tokyo
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- Fukuda Ryouichi [他] FUKUDA Ryouichi
- Department of Biotechnology, The University of Tokyo
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- OHTA Akinori
- Department of Biotechnology, The University of Tokyo
Abstract
Disruption of an <I>SCS2</I> ortholog impaired the growth of the alkane-assimilating yeast <I>Yarrowia lipolytica</I> on <I>n</I>-alkanes, particularly on <I>n</I>-decane, although the mRNA level of the <I>ALK1</I> gene encoding a highly inducible cytochrome P450ALK was not much affected. The same disruption did not cause inositol auxotrophy, implying that <I>Y. lipolytica</I> <I>SCS2</I> has a different function from its <I>Saccharomyces cerevisiae</I> counterpart.
Journal
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 72(8), 2219-2223, 2008-08-23
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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