Characterization of bZip-Type Transcription Factor AtfA with Reference to Stress Responses of Conidia of<i>Aspergillus nidulans</i>

  • HAGIWARA Daisuke
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University
  • ASANO Yoshihiro
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University
  • YAMASHINO Takafumi
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University
  • MIZUNO Takeshi
    Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

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  • Characterization of bZip-Type Transcription Factor AtfA with Reference to Stress Responses of Conidia of Aspergillus nidulans

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Microorganisms growing in natural habitats are permanently confronted with a wide variety of external stresses. In fungi, including Aspergillus nidulans, one of the general and ultimate strategies to survive in harsh habitats is the development of stress-tolerant conidia. In this study, we found that one of the basic-region leucine zipper transcription factors, named AtfA, plays a crucial role in the acquisition of tolerance against oxidative and heat stress on conidia, but not on mycelia, although this factor is not involved in asexual development per se.

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