The activity of a type 2 transmembrane serine protease, matriptase, is dependent solely on the catalytic domain

• KOJIMA Kenji

  Laboratory of Enzyme Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• TSUZUKI Satoshi

  Laboratory of Nutrition Chemistry Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• FUSHIKI Tohru

  Laboratory of Nutrition Chemistry Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• INOUYE Kuniyo

  Laboratory of Enzyme Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

書誌事項

タイトル別名

• The Activity of a Type II Transmembrane Serine Protease, Matriptase, Is Dependent Solely on the Catalytic Domain

抄録

Matriptase is a transmembrane serine protease comprising multiple domains in the extracellular region, including a stem domain and a catalytic domain. Using soluble matriptase variants containing entire extracellular domains or only the catalytic domain, the activity of this protease was found to depend solely on the catalytic domain. The stem domain had no significant effect on the activity.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 73 (2), 454-456, 2009

  公益社団法人 日本農芸化学会

キーワード

• catalytic domain
• enzyme activity
• matriptase
• membrane-type serine protease
• stem domain

詳細情報

• CRID: 1390282681454240768
• NII論文ID: 10027537869
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.80713
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 10166401
• Web Site: http://id.ndl.go.jp/bib/10166401
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10166401
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.80713
• 本文言語コード: en
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