Ultraviolet A-Induced Peroxidation of Phosphatidylcholine in Unilamellar Liposomes

• MAZARI Azzedine

  The United Graduate School of Agricultural Science, Gifu University

• IWAMOTO Satoshi

  The United Graduate School of Agricultural Science, Gifu University Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University

• YAMAUCHI Ryo

  The United Graduate School of Agricultural Science, Gifu University Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University

Abstract

Unilamellar liposomes of 1-palmitoyl-2-linoleoyl-3-sn-phosphatidylcholine (PLPC) were exposed to ultraviolet A (UVA) light at 37 °C. The UVA-induced PLPC peroxidation was inhibited by free radical scavengers, while singlet oxygen quenchers showed slight inhibition. When pre-existing hydroperoxides were reduced, UVA irradiation could not initiate the lipid peroxidation. The UVA-induced reaction of PLPC hydroperoxides with α-tocopherol produced addition products. The results indicate that UVA irradiation might dissociate hydroperoxides to alkoxyl and peroxyl radicals which stimulate lipid peroxidation.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 73 (5), 1212-1214, 2009

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• ultraviolet A
• phosphatidylcholine
• lipid peroxidation
• liposomes

Details

• CRID: 1390282681453705728
• NII Article ID: 10027541593
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.80879
• ISSN: 13476947
• ISSN: 09168451
• NDL BIB ID: 10235334
• Web Site: http://id.ndl.go.jp/bib/10235334
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10235334
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.80879
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed