The Occurrence of Matriptase C-Terminal Fragments on the Apical and Basolateral Sides of Madin-Darby Canine Kidney Epithelial Cells

• TSUZUKI Satoshi

  Laboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• MIYAKE Yuka

  Laboratory of Enzyme Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• INOUYE Kuniyo

  Laboratory of Enzyme Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

• FUSHIKI Tohru

  Laboratory of Nutrition Chemistry, Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

Abstract

Matriptase is a type II transmembrane serine protease. In the present study, matriptase C-terminal fragments containing the catalytic serine protease domain were found to occur on the apical and basolateral sides of Madin–Darby canine kidney epithelial cells transfected with a cDNA encoding the protease. This suggests that matriptase interacts with various potential substrates when expressed in simple epithelia.

Journal

• Bioscience, Biotechnology, and Biochemistry

  Bioscience, Biotechnology, and Biochemistry 73 (11), 2538-2540, 2009

  Japan Society for Bioscience, Biotechnology, and Agrochemistry

Keywords

• apical and basolateral domains
• C-terminal fragment
• distribution
• matriptase
• Madin–Darby canine kidney epithelial cells

Details

• CRID: 1390282681457285504
• NII Article ID: 10027548270
• NII Book ID: AA10824164
• DOI: 10.1271/bbb.90431
• ISSN: 13476947
• ISSN: 09168451
• NDL BIB ID: 10459846
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10459846
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.90431
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed