Synthesis of Annonacin Isolated from Annona densicoma

  • OASA Mayu
    Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University
  • HATTORI Yasunao
    Department of Chemistry, Graduate School of Medicinal Science, Kyoto Prefectural University of Medicine
  • KONNO Hiroyuki
    Department of Chemistry and Chemical Engineering, Graduate School of Science and Technology, Yamagata University
  • MAKABE Hidefumi
    Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University

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  • Synthesis of Annonacin Isolated from<i>Annona densicoma</i>

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Abstract

A total synthesis of annonacin (1) was accomplished by using versatile chiral building block 2 for synthesizing the mono-tetrahydrofuran (THF) annonaceous acetogenins.

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