Award reviews: Unique sugar metabolic pathways of bifidobacteria

• FUSHINOBU Shinya

  Department of Biotechnology, The University of Tokyo

書誌事項

タイトル別名

• Unique Sugar Metabolic Pathways of Bifidobacteria

抄録

Bifidobacteria have many beneficial effects for human health. The gastrointestinal tract, where natural colonization of bifidobacteria occurs, is an environment poor in nutrition and oxygen. Therefore, bifidobacteria have many unique glycosidases, transporters, and metabolic enzymes for sugar fermentation to utilize diverse carbohydrates that are not absorbed by host humans and animals. They have a unique, effective central fermentative pathway called bifid shunt. Recently, a novel metabolic pathway that utilizes both human milk oligosaccharides and host glycoconjugates was found. The galacto-N-biose/lacto-N-biose I metabolic pathway plays a key role in colonization in the infant gastrointestinal tract. These pathways involve many unique enzymes and proteins. This review focuses on their molecular mechanisms, as revealed by biochemical and crystallographic studies.

収録刊行物

• Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ

  Ｂｉｏｓｃｉｅｎｃｅ，　Ｂｉｏｔｅｃｈｎｏｌｏｇｙ，　ａｎｄ　Ｂｉｏｃｈｅｍｉｓｔｒｙ 74 (12), 2374-2384, 2010

  公益社団法人 日本農芸化学会

キーワード

• bifidobacteria
• lacto-<I>N</I>-biose I
• galacto-<I>N</I>-biose
• glycoside hydrolase
• phosphorylase

詳細情報

• CRID: 1390001206479296768
• NII論文ID: 10027727681
• NII書誌ID: AA10824164
• DOI: 10.1271/bbb.100494
• COI: 1:STN:280:DC%2BC3M%2FntVGltQ%3D%3D
• ISSN: 13476947
• ISSN: 09168451
• NDL書誌ID: 10928473
• PubMed: 21150123
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10928473
• Web Site: http://www.tandfonline.com/doi/pdf/10.1271/bbb.100494
• Web Site: https://search.jamas.or.jp/link/ui/2011287532
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
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