Amyloid Imaging Using High-Field Magnetic Resonance
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- AMATSUBO Tomone
- Molecular Neuroscience Research Center, Shiga University of Medical Science Japan Science and Technology Agency (JST) Innovation Satellite
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- YANAGISAWA Daijiro
- Molecular Neuroscience Research Center, Shiga University of Medical Science Japan Science and Technology Agency (JST) Innovation Satellite
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- MORIKAWA Shigehiro
- Department of Fundamental Nursing, Shiga University of Medical Science
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- TAGUCHI Hiroyasu
- Molecular Neuroscience Research Center, Shiga University of Medical Science
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- TOOYAMA Ikuo
- Molecular Neuroscience Research Center, Shiga University of Medical Science
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Abstract
The formation of senile plaques followed by deposition of amyloid β peptides (Aβ) are the earliest pathological changes of Alzheimer's disease (AD); thus, detection of the plaques remains the most important early diagnostic indicator of AD. Amyloid imaging is a noninvasive technique for visualizing senile plaques in the brains of patients with Alzheimer's using positron emission tomography (PET) or magnetic resonance (MR) imaging. Several types of probes have been developed for PET, but few ligands have been developed specifically for MR imaging detection of amyloid plaques. This review presents recent advances in amyloid imaging using MR imaging and includes our studies.<br>
Journal
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- Magnetic Resonance in Medical Sciences
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Magnetic Resonance in Medical Sciences 9 (3), 95-99, 2010
Japanese Society for Magnetic Resonance in Medicine
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Details 詳細情報について
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- CRID
- 1390282680173378304
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- NII Article ID
- 10027851175
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- NII Book ID
- AA11648770
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- COI
- 1:CAS:528:DC%2BC3cXhtlaqurzP
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- ISSN
- 18802206
- 13473182
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- PubMed
- 20885081
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed