SRD Outstanding Research Award 2010: Study on the mechanism of maternal imprinting during oocyte growth
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- OBATA Yayoi
- Department of BioScience, Tokyo University of Agriculture
書誌事項
- タイトル別名
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- Study on the Mechanism of Maternal Imprinting During Oocyte Growth
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抄録
In mammals, both parental genomes are essential for normal ontogeny because epigenetic modifications imposed in the parents' gametes lead to parent-of-origin specific gene expression in their offspring. These phenomena are referred to as genomic imprinting. It has been shown that maternal imprinting is established during oocyte growth, lack of maternal imprinting in zygotes leads to early embryonic death, and in vitro system that allows establishment of maternal imprinting is developed. In this review, I describe the history of the discovery of genomic imprinting, the regulatory mechanisms of mammalian development by maternal imprinting, and the molecular mechanisms of genomic imprinting.<br>
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 57 (1), 1-8, 2011
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390001206337731072
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- NII論文ID
- 10027900689
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- NII書誌ID
- AA10936678
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 10991495
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可