ＡＣＥ阻害剤による口腔底および顎下部の晩発性血管浮腫例

DOI Web Site 参考文献34件
  • 吉福 孝介
    鹿児島大学大学院医歯学総合研究科　先進治療科学専攻感覚器病学聴覚頭頸部疾患学
  • 大堀 純一郎
    鹿児島大学大学院医歯学総合研究科　先進治療科学専攻感覚器病学聴覚頭頸部疾患学
  • 黒野 祐一
    鹿児島大学大学院医歯学総合研究科　先進治療科学専攻感覚器病学聴覚頭頸部疾患学

書誌事項

タイトル別名
  • Late-onset Oral-floor Angioedema and Submandibular Lesion Caused by Angiotensin-converting Enzyme Inhibitor
  • 臨床 ACE阻害剤による口腔底および顎下部の晩発性血管浮腫例
  • リンショウ ACE ソガイザイ ニ ヨル コウクウテイ オヨビ ガクカブ ノ バンパツセイ ケッカン フシュレイ

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抄録

Angioedema, occurring in the pharynx and induced by Angiotensin-Converting Enzyme inhibitor (ACEi), is life-threatening and requires emergency treatment. A 69-year old woman referred for recurrent oral edema and neck swelling had been taking oral ACEi due to hypertension for over 5 years. She had no history of food allergy or marked family history. Examination showed soft diffuse bilateral oral floor swelling with normal-color mucosa. She did not report dyspnea, dysphagia, or pain. Blood tests showed normal levels of C3, C4, CH50, and C1 inhibitor function. Although most ACEi-associated angioedema occurs within the first week of administration, we diagnosed angioedema due to ACEi based on laboratory results. Once ACEi administration was stopped, oral floor swelling disappeared.<br> It is thus important in angioedema treatment to check oral medication.<br>

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