Primary Germinoma in the Medulla Oblongata : Case Report

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Author(s)

    • YASUHARA Takao
    • Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    • ICHIKAWA Tomotsugu
    • Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    • MIYOSHI Yasuyuki
    • Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    • KUROZUMI Kazuhiko
    • Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    • MARUO Tomoko
    • Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    • YANAI Hiroyuki
    • Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
    • DATE Isao
    • Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

Abstract

A 27-year-old woman presented with a case of primary medulla oblongata germinoma manifesting as sleep apnea, aspiration pneumonia, and left hemiparesis. Magnetic resonance (MR) imaging revealed a dorsal mass in the medulla oblongata with heterogeneous enhancement by gadolinium (Gd). Emergent biopsy and foramen magnum decompression with C1 laminectomy were performed because of rapid worsening of her symptoms. The histological diagnosis was germinoma. Subsequently she received chemoradiation therapy with subsequent amelioration of her neurological deficits and disappearance of enhancement on MR imaging with Gd. Primary medulla oblongata germinoma is rare and difficult to diagnose preoperatively. However, correct diagnosis and subsequent adequate chemoradiation therapy is possible by understanding the common characteristics of the disease. Germinoma should be included in the differential diagnosis of midline medullary lesion in young patients, and biopsy should be considered.<br>

Journal

  • Neurologia medico-chirurgica

    Neurologia medico-chirurgica 51(4), 326-329, 2011-04-15

    The Japan Neurosurgical Society

References:  14

Codes

  • NII Article ID (NAID)
    10028105421
  • NII NACSIS-CAT ID (NCID)
    AN00358613
  • Text Lang
    ENG
  • Article Type
    NOT
  • ISSN
    04708105
  • Data Source
    CJP  J-STAGE 
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