2. Amyloidosis

• Takahashi Naoki

  Division of Nephrology, Department of General Medicine, Faculty of Medical Sciences, University of Fukui

• Kimura Hideki

  Division of Nephrology, Department of General Medicine, Faculty of Medical Sciences, University of Fukui

• Yoshida Haruyoshi

  Division of Nephrology, Department of General Medicine, Faculty of Medical Sciences, University of Fukui

• Naiki Hironobu

  Division of Molecular Pathology, Department of General Medicine, Faculty of Medical Sciences, University of Fukui

Bibliographic Information

Other Title

• 2．アミロイドーシス
• アミロイドーシス

Abstract

アミロイドーシスは，全身の臓器の細胞外領域に難溶性のアミロイド線維が沈着し，機能障害を引き起こす一連の疾患群で，腎臓は機能障害が好発する臓器である．腎アミロイドーシスは，様々な程度の蛋白尿や腎機能低下を伴い，高齢者のネフローゼ症候群の原因になっている．パラプロテイン血症に伴う腎アミロイドーシスはALアミロイドーシスがほとんどであるので，本稿ではALアミロイド線維形成のメカニズムを踏まえて知見を概説する．<br>

Journal

• Nihon Naika Gakkai Zasshi

  Nihon Naika Gakkai Zasshi 100 (5), 1282-1288, 2011

  The Japanese Society of Internal Medicine

Keywords

• light chain
• free light chain
• AL amyloidosis
• amyloid fibril

Details

• CRID: 1390282681421402368
• NII Article ID: 10029097141
• NII Book ID: AN00195836
• DOI: 10.2169/naika.100.1282
• COI: 1:CAS:528:DC%2BC3MXnvVersbs%3D
• ISSN: 18832083
• ISSN: 00215384
• NDL BIB ID: 11131435
• PubMed: 21702145
• Web Site: http://id.ndl.go.jp/bib/11131435
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I11131435
• Web Site: https://www.jstage.jst.go.jp/article/naika/100/5/100_1282/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2011248898
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed