The Number Needed to Invite（NNI）for Breast Cancer Mammography Screening in Japan

DOI 1 Citations 25 References
  • Saika Kumiko
    Center for Cancer Control and Information Services, National Cancer Center Research Center for Cancer Prevention and Screening, National Cancer Center
  • Saito Hiroshi
    Research Center for Cancer Prevention and Screening, National Cancer Center
  • Ohuchi Noriaki
    Department of Surgical Oncology, Graduate School of Medicine, Tohoku University
  • Sobue Tomotaka
    Center for Cancer Control and Information Services, National Cancer Center

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  • 乳癌死ひとりを回避するのに必要な日本人女性のマンモグラフィ検診必要対象者数

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Abstract

In 2009, the US Preventive Services Task Force (USPSTF) recommended that the decision to start regular screening mammography (MMG) before the age of 50 years should be an individual one. They calculated the number needed to invite (NNI) to screening to prevent one death from breast cancer (BC) and concluded that the net benefit is smaller for women aged 40-49yr with its larger NNI than that for women aged 50-59yr. Estimating the NNI by age group is also important in Japan. There has been a need to estimate absolute differences in BC cumulative mortality between women with and without MMG. Since such data are unavailable, we assumed that BC mortality for Japanese women would be the same as that for women without MMG, and that the relative risks were the same as those reported by the USPSTF. Comparison of NNI in Japan with the USPSTF report yielded results that were similar for women aged 40-49yr and 50-59yr, whereas the NNI in Japan was double that reported by the USPSTF for women aged 60-69yr. In Japan, studies for evaluating the balance between the benefits and drawbacks of MMG are needed.

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