A case of borderline clear cell adenofibroma

DOI 8 References
  • NAKAMURA Masaru
    Department of Obstetrics and Gynecology, Tokyo Dental College Ichikawa General Hospital
  • OGAWA Mariko
    Department of Obstetrics and Gynecology, Tokyo Dental College Ichikawa General Hospital
  • FUKUDA Masami
    Department of Pathology, Tokyo Dental College Ichikawa General Hospital
  • GIBO Kazuo
    Department of Pathology, Tokyo Dental College Ichikawa General Hospital
  • SAITO Junichi
    Department of Pathology, Tokyo Dental College Ichikawa General Hospital
  • TANAKA Yoichi
    Department of Pathology, Tokyo Dental College Ichikawa General Hospital
  • MIYAUCHI Jun
    Department of Pathology, Tokyo Dental College Ichikawa General Hospital
  • TAKAMATSU Kiyoshi
    Department of Obstetrics and Gynecology, Tokyo Dental College Ichikawa General Hospital

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Other Title
  • 卵巣境界悪性明細胞腫瘍における腫瘍割面捺印細胞診の有用性

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Abstract

Background : Clear cell ovarian borderline tumor is rare, reported mostly as adenofibroma. We report a case whose diagnosis could not be determined preoperatively, particularly for malignant potential.<br>Case : A 72-year-old woman found in a medical checkup to have an abdominal mass was not found in cervical or endometrial cytology to have a malignancy. Tumor marker CA125 was 192 U/ml. Magnetic resonance imaging (MRI) showed a solid right ovarian tumor with a low at T2-weighted signal, necessitating total abdominal hysterectomy and bilateral salpingo-oophorectomy. The tumor had a yellowish-white solid part and a cystic part. Imprint smear cytology showed atypical glandular cells with coarse chromatin clumping. Microscopic tumor examination showed clear cell borderline adenofibroma.<br>Conclusion : Imprint smear cytology may be useful in supplementarily confirming clear cell borderline adenofibroma diagnosis.

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