Characteristics and Predictors of Drug-Eluting Stent Thrombosis - Results From the Multicenter Korea Stent Thrombosis (KoST)' Registry -
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- Park Kyung Woo
- Cardiovascular Center, Seoul National University Main Hospital
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- Hwang Seok-Jae
- Kyungsang National University Hospital Samsung Medical Center
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- Kwon Dong-A
- Cardiovascular Center, Seoul National University Main Hospital
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- Oh Byung-Hee
- Cardiovascular Center, Seoul National University Main Hospital
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- Park Young-Bae
- Cardiovascular Center, Seoul National University Main Hospital
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- Chae In-Ho
- Bundang Hospital
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- Gwon Hyeon-Cheol
- Samsung Medical Center
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- Park Seung-Jung
- Asan Medical Center
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- Seung Ki Bae
- The Catholic University St Mary's Hospital
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- Ahn Taehoon
- Gachon University Gil Medical Center
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- Yoon Jung-Han
- Wonju Christian Hospital
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- Jang Yang-Soo
- Yonsei University Severance Hospital
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- Jeong Myung-Ho
- Chonnam National University Hospital
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- Tahk Seung-Jea
- Ajou University Medical Center
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- Kim Hyo-Soo
- Cardiovascular Center, Seoul National University Main Hospital
書誌事項
- タイトル別名
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- – Results From the Multicenter `Korea Stent Thrombosis (KoST)' Registry –
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Background: Previous studies have reported possible predictors of drug-eluting stent thrombosis (ST), but data for Asians are relatively limited. This study was performed to elucidate clinical predictors of ST in Koreans. Methods and Results: From May 2003 to May 2007, consecutive patients presenting with ST were enrolled from 10 cardiovascular centers in Korea. They were compared with 2,192 controls (3,223 lesions) who had received percutaneous coronary intervention with at least 6 months of follow-up without ST. On multivariate analysis, acute myocardial infarction (AMI) as initial diagnosis, drug-eluting stents (DES) in-stent restenosis (ISR), low ejection fraction (EF), small stent diameter, left anterior descending artery intervention, and young age were independent predictors of total ST. When divided into early (ST within 30 days of index procedure) and delayed ST (ST after 30 days of index procedure), low EF, small stent diameter, DES ISR and AMI as initial diagnosis were universal risks for both early and delayed ST. The time from antiplatelet agent discontinuation to ST occurrence was significantly shorter in late compared with very late ST. Conclusions: Predictors of ST may be slightly different for early vs. delayed ST. However, low EF, small stent diameter, DES ISR lesion, and AMI as initial diagnosis were universal risk factors for both early and delayed ST cases. The relationship between antiplatelet agent discontinuation and ST occurrence seems stronger in late compared with very late ST. (Circ J 2011; 75: 1626-1632)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 75 (7), 1626-1632, 2011
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680080489472
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- NII論文ID
- 10029126486
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- NII書誌ID
- AA11591968
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- COI
- 1:STN:280:DC%2BC3Mjlt1Wqsw%3D%3D
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- ISSN
- 13474820
- 13469843
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- PubMed
- 21628837
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- PubMed
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