Toxicogenomics/proteomics report: Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury
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- Hwang Gi-Wook
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
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- Lee Jin-Yong
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
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- Ryoke Katsunori
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
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- Matsuyama Fujio
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
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- Kim Jong-Mu
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
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- Takahashi Tsutomu
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
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- Naganuma Akira
- Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences,Tohoku University
書誌事項
- タイトル別名
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- Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury
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抄録
To elucidate the molecular mechanism involved in methylmercury-induced cerebellar disorder, we performed DNA microarray analysis of the cerebellum of methylmercury-treated mice. The expression levels of 21 genes were elevated 2-fold or higher in response to methylmercury, including many genes encoding proteins involved in inflammatory reactions associated with chemokines. The expression levels of 11 genes were reduced by half or more in response to methylmercury.
収録刊行物
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- The Journal of Toxicological Sciences
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The Journal of Toxicological Sciences 36 (3), 389-391, 2011
一般社団法人 日本毒性学会
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詳細情報 詳細情報について
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- CRID
- 1390001204902111744
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- NII論文ID
- 10029136086
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- NII書誌ID
- AN00002808
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- COI
- 1:CAS:528:DC%2BC3MXpsVKhs7w%3D
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- ISSN
- 18803989
- 03881350
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- NDL書誌ID
- 11145577
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- PubMed
- 21628967
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可