北海道の妊婦の全血中POPs系農薬の濃度 : 環境と子どもの健康に関する北海道研究  [in Japanese] Concentrations of Persistent Organochlorine Pesticides in Whole Blood of Pregnant Women in Hokkaido Study on Environment and Children's Health  [in Japanese]

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Author(s)

Abstract

Objectives: This study was performed to evaluate the levels of exposure to persistent organochlorine pesticides in pregnant women in Hokkaido.<br> Methods: Whole-blood samples were obtained from 70 pregnant women aged 17 to 39 years in Hokkaido and analyzed to quantify 29 organochlorine pesticides by gas chromatography/negative ion chemical ionization mass spectrometry and gas chromatography/high-resolution mass spectrometry.<br> Results: Among 29 target compounds, 20 were detected in the whole-blood samples. Mirex, Parlar-26, and Parlar-50, which have never been used in Japan, were identified in all samples, as well as 11 compounds that have been used in Japan. Log-transformed concentrations of compounds with detection rates above 60% linearly correlated with each other (p<0.01). <i>p,p</i>′-DDE exhibited the highest concentration, with a geometric mean of 730 pg/g wet weight. From the results of the Jonckheere-Terpstra trend test, body weight or age was positively associated with the concentrations of several compounds.<br> Conclusions: We detected 22 organochlorine pesticides including pesticides with no history of use in Japan in the whole-blood samples from pregnant women in Hokkaido. Through long-distance transport mechanisms, these pollutants may distribute widely, and further surveillance of human blood, in addition to foods and the environment, should be conducted.<br>

Journal

  • Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)

    Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) 66(1), 95-107, 2011-01-15

    The Japanese Society for Hygiene

References:  46

Codes

  • NII Article ID (NAID)
    10029363979
  • NII NACSIS-CAT ID (NCID)
    AN00185923
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    00215082
  • NDL Article ID
    11003551
  • NDL Source Classification
    ZS17(科学技術--医学--衛生学・公衆衛生)
  • NDL Call No.
    Z19-194
  • Data Source
    CJP  NDL  J-STAGE 
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