Depression and Outcomes in Hospitalized Japanese Patients With Cardiovascular Disease - Prospective Single-Center Observational Study -
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- Suzuki Tsuyoshi
- Department of Cardiology, Tokyo Women's Medical University
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- Shiga Tsuyoshi
- Department of Cardiology, Tokyo Women's Medical University
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- Kuwahara Kazue
- Department of Cardiology, Tokyo Women's Medical University Department of Psychiatry, Tokyo Women's Medical University
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- Kobayashi Sayaka
- Department of Psychiatry, Tokyo Women's Medical University
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- Suzuki Shinichi
- Faculty of Human Sciences, Waseda University
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- Nishimura Katsuji
- Department of Psychiatry, Tokyo Women's Medical University
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- Suzuki Atsushi
- Department of Cardiology, Tokyo Women's Medical University
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- Omori Hisako
- Department of Cardiology, Tokyo Women's Medical University
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- Mori Fumiaki
- Department of Cardiology, Tokyo Women's Medical University
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- Ishigooka Jun
- Department of Psychiatry, Tokyo Women's Medical University
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- Kasanuki Hiroshi
- Faculty of Science and Engineering, Waseda University
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- Hagiwara Nobuhisa
- Department of Cardiology, Tokyo Women's Medical University
書誌事項
- タイトル別名
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- – Prospective Single-Center Observational Study –
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Background: Several studies have suggested that depression poses a risk in cardiovascular patients. The aim of the present study was to evaluate the prevalence of depression and its effect on cardiovascular events and mortality in Japanese inpatients with cardiovascular disease. Methods and Results: A total of 505 patients hospitalized with cardiovascular disease (28% female; mean age, 61±14 years; 31% ischemic heart disease; 47% New York Heart Association [NYHA] class II-IV; 25% implantation of pacing devices) were enrolled in the present prospective observational study. The Zung Self-Rating Depression Scale (SDS) was used to screen for depression. The primary outcome was the time to death or cardiovascular event, and the secondary outcome was death. In total, 109 patients (22%) were diagnosed with depression (Zung SDS index score ≥60). NYHA class III/IV, defibrillator implantation, and being unmarried were independently associated with depression. During an average follow-up period of 38±15 months, 92 patients (18%) reached the primary outcome. There was a higher incidence of the primary outcome in patients with depression than in those who were not depressed (P<0.01). Depressed patients had a significantly higher rate of mortality than non-depressed patients (P<0.01). Depression was an independent predictor of the primary outcome (hazard ratio, 2.25; 95% confidence interval: 1.30-3.92, P<0.01). Conclusions: Depression was not uncommon in Japanese inpatients with cardiovascular disease and was associated with cardiovascular outcomes. (Circ J 2011; 75: 2465-2473)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 75 (10), 2465-2473, 2011
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205101740160
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- NII論文ID
- 10029459801
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- NII書誌ID
- AA11591968
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- COI
- 1:STN:280:DC%2BC3MfltlyksA%3D%3D
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- ISSN
- 13474820
- 13469843
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- PubMed
- 21791870
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
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- 使用不可