Modulation of sweet taste sensitivity by orexigenic and anorexigenic factors

• Jyotaki Masafumi

  Section of Oral Neuroscience, Kyushu University, Graduate School of Dental Sciences, Fukuoka, Japan

• Shigemura Noriatsu

  Section of Oral Neuroscience, Kyushu University, Graduate School of Dental Sciences, Fukuoka, Japan

• Ninomiya Yuzo

  Section of Oral Neuroscience, Kyushu University, Graduate School of Dental Sciences, Fukuoka, Japan

Abstract

The present study summarized recent findings on roles of leptin and endocannabinoids as modulators of the peripheral components of sweet taste. The positive effect of endocannabinoids on sweet sensitivity was opposed to that of leptin which suppresses sweet sensitivity. Leptin and endocannabinoids, therefore, not only regulate food intake via central nervous systems but also may modulate palatability of foods by altering peripheral sweet taste responses via their cognate receptors. Orexigenic and anorexigenic factors such as endocannnabinoids and leptin may affect energy homeostasis by regulating taste sensitivity.

Journal

• Endocrine Journal

  Endocrine Journal 57 (6), 467-475, 2010

  The Japan Endocrine Society

Keywords

• Sweet taste
• Leptin
• Endocannabinoids
• Modulation
• Energy homeostasis

Details

• CRID: 1390001206299503488
• NII Article ID: 10029584967
• NII Book ID: AA10901436
• DOI: 10.1507/endocrj.k10e-095
• ISSN: 13484540
• ISSN: 09188959
• Web Site: http://www.jstage.jst.go.jp/article/endocrj/57/6/57_K10E-095/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2010282875
• Text Lang: en
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed