Domain Formation and Molecular Diffusion in Supported Lipid Bilayers on Oxide Surfaces
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- Tero Ryugo
- The Electronics-Inspired Interdisciplinary Research Institute, Toyohashi University of Technology
Bibliographic Information
- Other Title
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- 酸化物基板表面上の支持平面脂質二重膜内でのドメイン形成と分子拡散挙動のその場観察
- サンカブツ キバン ヒョウメン ジョウ ノ シジ ヘイメン シシツ ニジュウ マク ナイ デ ノ ドメイン ケイセイ ト ブンシ カクサン キョドウ ノ ソノバ カンサツ
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Abstract
Dynamics in lipid bilayers such as two dimensional domain formation and lateral molecular transportation are crucial factors in cell membrane reactions. In this review several recent studies about the domain formations and molecular diffusion using supported planar lipid bilayers (SLBs) are introduced. SLBs exist at the interface between solid substrates and aqueous solutions, 1 ∼ 2 nm away from the substrate. The fluidity of the membrane remains while the membrane is still affected by the structure and the physical properties of the substrate surface. Two dimensional domain structures on the lateral order of several micrometers in SLB are affected by the atomic scale structures of the substrate. At the latter half of this review, the method of single molecule tracking free from the restriction of substrate materials is described. Lipid diffusions in SLBs on opaque silicon wafer and high refractive TiO2 substrate were observed in situ and the diffusion coefficients were successfully obtained.
Journal
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- MEMBRANE
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MEMBRANE 36 (1), 16-23, 2011
THE MEMBRANE SOCIETY OF JAPAN
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Keywords
Details 詳細情報について
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- CRID
- 1390001206423322496
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- NII Article ID
- 10029601592
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- NII Book ID
- AN0023215X
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- COI
- 1:CAS:528:DC%2BC3MXivVWrtLg%3D
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- ISSN
- 18846440
- 03851036
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- NDL BIB ID
- 10992711
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed