Ruthenium-catalyzed Oxidative Alkenylation of Arenes via Regioselective C–H Bond Cleavage Directed by a Nitrogen-containing Group

  • Yuto Hashimoto
    Department of Applied Chemistry, Faculty of Engineering, Osaka University
  • Takumi Ueyama
    Department of Applied Chemistry, Faculty of Engineering, Osaka University
  • Tatsuya Fukutani
    Department of Applied Chemistry, Faculty of Engineering, Osaka University
  • Koji Hirano
    Department of Applied Chemistry, Faculty of Engineering, Osaka University
  • Tetsuya Satoh
    Department of Applied Chemistry, Faculty of Engineering, Osaka University
  • Masahiro Miura
    Department of Applied Chemistry, Faculty of Engineering, Osaka University

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<jats:title>Abstract</jats:title> <jats:p>Direct alkenylation of 1-phenylpyrazoles with alkenes such as acrylates accompanied by regioselective C–H bond cleavage proceeds efficiently under ruthenium catalysis in the presence of a copper oxidant. The procedure is also applicable to 2-phenylbenzothiazole and benzanilide.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 40 (10), 1165-1166, 2011-09-28

    Oxford University Press (OUP)

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