Characteristics and Utilization of Cyclic Bacteriocins

• ARAKAWA Kensuke

  Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University

• KAWAI Yasushi

  Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University

• SAITO Tadao

  Laboratory of Animal Products Chemistry, Graduate School of Agricultural Science, Tohoku University

Bibliographic Information

Other Title

• 環状バクテリオシンの発見とその利用性

Abstract

In 1994, a new bacteriocin, enterocin AS-48, produced by Enterococcus faecalis subsp. liquefaciens S-48, with a cyclic structure arising from a head-to-tail linkage was first discovered. After that, seven research papers concerning cyclic bacteriocins have been presented. In 2003, a new classification system of bacteriocins in which the cyclic bacteriocins are “class V” was proposed. Structural and genetic characteristics and antimicrobial mechanisms are different among the class V bacteriocins, but all of them have high stability against heat and pH and high antimicrobial activity. At present, researches on mechanism of their enzymatic cyclizations which give them their high stability and bioactivity are taking place, and novel utilization of these cyclic bacteriocins in the future is expected.

Journal

• Japanese Journal of Lactic Acid Bacteria

  Japanese Journal of Lactic Acid Bacteria 16 (2), 67-74, 2005

  Japan Society for Lactic Acid Bacteria

Keywords

• bacteriocin
• cyclic peptide
• head-to-tail cyclization
• class V
• gassericin A

Details

• CRID: 1390282680434645376
• NII Article ID: 130004629004
• NII Article ID: 10029750856
• NII Book ID: AA11505820
• DOI: 10.4109/jslab1997.16.67
• ISSN: 1343327X
• ISSN: http://id.crossref.org/issn/1343327X
• Web Site: https://search.jamas.or.jp/link/ui/2007012899
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed