Role of S-layer Proteins in the Adhesion of<br> <i>Lactobacillus</i> to Mucosal Surface of Intestine

  • Mukai Takao
    School of Veterinary Medicine and Animal Science, Kitasato University

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  • Lactobacillus乳酸菌におけるS‐layer様タンパク質が介在する腸上皮への付着

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Abstract

S-layers composed of protein monomers arranged in crystalline arrays have been found in both gram-positive and gram-negative bacteria, including Lactobacillus species. The function of S-layer has not been accurately defined. Several Lactobacillus species found in intestinal tract have been shown to express S-layer., and it has been suggested that certain lactobacillar S-layer is participated in the adhesion to mucosal surface of intestine. It is possible that Lactobacillus strains expressing S-layer that recognizes a specific receptor are applied to the protection of pathogens that recognize the same receptor. We describe here typical features of S-layers of Lactobacillus and role of S-layer of Lactobacillus kitasatonis, which has been proposed as a new species by our laboratory, in the adhesion to mucosal surface of intestine.

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