Longitudinal Risk of Cardiovascular Events in Relation to Depression Symptoms After Discharge Among Survivors of Myocardial Infarction - Osaka Acute Coronary Insufficiency Study (OACIS) -

  • Shiozaki Mariko
    Applied Sociology Department, Kinki University
  • Iso Hiroyasu
    Public Health, Department of Social and Environmental Health, Osaka University Graduate School of Medicine
  • Ohira Tetsuya
    Public Health, Department of Social and Environmental Health, Osaka University Graduate School of Medicine
  • Nakatani Daisaku
    Cardiovascular Medicine, Osaka University Graduate School of Medicine
  • Shimizu Masahiko
    Cardiovascular Medicine, Osaka University Graduate School of Medicine
  • Sakata Yasuhiko
    Cardiovascular Medicine, Osaka University Graduate School of Medicine
  • Komuro Issei
    Cardiovascular Medicine, Osaka University Graduate School of Medicine
  • Sato Hiroshi
    Cardiovascular Medicine, Osaka University Graduate School of Medicine School of Human Welfare Studies, Kwansei Gakuin University

Bibliographic Information

Other Title
  • Longitudinal risk of cardiovascular events in relation to depression symptoms after discharge among survivors of myocardial infarction. Osaka Acute Coronary Insufficiency Study
  • – Osaka Acute Coronary Insufficiency Study (OACIS) –

Search this article

Abstract

Background: The purpose of this study was to investigate the association between depression symptoms 1 year after onset and subsequent cardiovascular events among survivors of myocardial infarction (MI). Methods and Results: The participants were recruited from respondents to a district-based survey known as the Osaka Acute Coronary Insufficiency Study. Of 4,271 eligible MI patients, 1,951 completed the Zung Self-Rating Depression Scale (SDS) at their 1-year follow-up examination. After excluding patients who experienced cardiovascular events within 1 year, the data for the remaining 1,307 male patients and 280 female patients were analyzed. Among male patients, depression status at 1 year after onset of MI was significantly related to risk of subsequent cardiovascular events throughout the follow-up period (median 2.9 years). The male patients in the top vs. bottom tertiles of SDS scores (top tertile being ≥42) had a multivariable-adjusted hazard ratio (HR) of 1.67 (95% confidence interval (CI) 1.01-2.77, P=0.04), and a 1-SD increment in SDS score was significantly related to a heightened risk of cardiovascular events, with a multivariable-adjusted HR of 1.30 (95%CI 1.07-1.58, P=0.01). There were no significant associations between SDS scores and cardiovascular events among female patients. Conclusions: Depression symptoms 1 year after onset of MI are a significant predictor of subsequent cardiovascular events for male patients. (Circ J 2011; 75: 2878-2884)<br>

Journal

  • Circulation Journal

    Circulation Journal 75 (12), 2878-2884, 2011

    The Japanese Circulation Society

Citations (9)*help

See more

References(57)*help

See more

Details 詳細情報について

Report a problem

Back to top