Percutaneous Transluminal Pulmonary Angioplasty Markedly Improves Pulmonary Hemodynamics and Long-Term Prognosis in Patients With Chronic Thromboembolic Pulmonary Hypertension

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Author(s)

    • SUGIMURA Koichiro
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • FUKUMOTO Yoshihiro
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • SATOH Kimio
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • NOCHIOKA Kotaro
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • MIURA Yutaka
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • AOKI Tatsuo
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • TATEBE Shunsuke
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
    • SHIMOKAWA Hiroaki
    • Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine

Abstract

<b><i>Background:</i></b> Distal-type chronic thromboembolic pulmonary hypertension (CTEPH) is a fatal disease for which a new therapeutic strategy needs to be developed. We examined the effects of percutaneous transluminal pulmonary angioplasty (PTPA). <b><i>Methods and Results:</i></b> We prospectively enrolled 12 patients with distal-type CTEPH. After stabilizing their condition with pulmonary vasodilators, we then performed PTPA, which markedly improved pulmonary hemodynamics and pulmonary artery structure, as confirmed by angiography and optical coherence tomography, and also significantly improved their long-term prognosis compared with 39 historical controls. <b><i>Conclusions:</i></b> PTPA is a promising therapeutic option for distal-type CTEPH. (<i>Circ J</i> 2012; <b>76:</b> 485-488)<br>

Journal

  • Circulation Journal

    Circulation Journal 76(2), 485-488, 2012-01-25

    The Japanese Circulation Society

References:  9

Cited by:  4

Codes

  • NII Article ID (NAID)
    10030036102
  • NII NACSIS-CAT ID (NCID)
    AA11591968
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13469843
  • Data Source
    CJP  CJPref  J-STAGE 
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