ペリプラズム側構造から見たべん毛モーター構築とモーターの活性化機構

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タイトル別名
  • Assembly and Activation Mechanism of the Flagellar Stator Revealed by the Crystal Structure of Its Periplasmic Region
  • ペリプラズムガワ コウゾウ カラ ミタ ベンモウ モーター コウチク ト モーター ノ カッセイカ キコウ

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抄録

Bacterial flagellar motor is an ion-driven supramolecular nanomachine embedded in the cell envelope. Rotor-stator interaction that couples to the specific ion translocation through the stator channel is the nature of torque generation. To produce fully functional motor, multiple stator complexes must be incorporated around the rotor at appropriate places. However, such stator assembly mechanism has not been investigated by the structural point of view. Here we describe stator assembly and activation mechanism revealed from the crystal structure of a motor component located in the periplasmic space, suggesting the dynamic conformational changes in the stator during its assembly-coupled activation.<br>

収録刊行物

  • 生物物理

    生物物理 52 (1), 018-021, 2012

    一般社団法人 日本生物物理学会

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