多房性胸腺嚢胞に合併した胸腺類基底細胞癌の一切除例 A surgical case of thymic cancer associated with multilocular thymic cysts

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著者

    • 迫田 京佳 SAKODA Kyoka
    • 佐賀大学医学部附属病院 胸部・心臓血管外科 Department of Cardiovascular and Chest Surgery, Faculty of Medicine, Saga University
    • 武田 雄二 TAKEDA Yuji
    • 佐賀大学医学部附属病院 胸部・心臓血管外科 Department of Cardiovascular and Chest Surgery, Faculty of Medicine, Saga University
    • 光岡 正浩 MITSUOKA Masahiro
    • 佐賀大学医学部附属病院 胸部・心臓血管外科 Department of Cardiovascular and Chest Surgery, Faculty of Medicine, Saga University

抄録

症例は37歳,女性.検診にて胸部X線写真上右肺門部に前縦隔腫瘍を疑う異常影を指摘された.胸部CTおよびMRI検査で,多房性胸腺嚢胞および腫瘍性病変の合併を疑い,胸腔鏡補助下胸腺・胸腺腫瘍摘出術を施行した.腫瘍の一部が中葉中枢側に浸潤していたため,中葉を合併切除した.術後病理診断は多房性胸腺嚢胞に合併した胸腺類基底細胞癌;basaloid carcinomaであった.術後放射線療法を追加し,現在術後2年が経過するも無再発生存中である.胸腺発生のbasaloid carcinomaは低悪性度群に分類されるものの非常に稀な疾患で,これまでに自験例を含め37例が報告されているのみである.診断,治療,生物学的特性に関する文献的考察を加えて報告する.

This patient was a 37-year-old woman. An abnormal shadow was found in the hilar portion on a chest radiograph during examination. The tumor showed a lobular shape on chest CT and MRI. The tumor consisted of multiple cysts and substantial parts. Multilocular thymic cysts merging with a tumor was doubtful. A thymothymectomy with thoracoscopically assisted surgery was performed for this mediastinal tumor. A part of the tumor had invaded the middle lobe and required combined resection. The postoperative pathological diagnosis was basaloid carcinoma, which developed in the background of a multilocular thymic cyst. We added postoperative radiotherapy to the treatment of this patient, and there has been no recurrence after two postoperative years. Thymic basaloid carcinoma, including our case, is a very rare disease classified in the low-malignancy group; 37 cases have been reported to date. We discuss its diagnosis, treatment, and considerations of its biochemical characteristics from the literature.

収録刊行物

  • 日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery

    日本呼吸器外科学会雑誌 = The journal of the Japanese Association for Chest Surgery 26(2), 131-136, 2012-03-15

    特定非営利活動法人 日本呼吸器外科学会

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各種コード

  • NII論文ID(NAID)
    10030125515
  • NII書誌ID(NCID)
    AN10467885
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    09190945
  • データ提供元
    CJP書誌  J-STAGE 
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