Intracerebral Hemorrhage in Patients With Chronic Liver Disease

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著者

    • HOYA Katsumi
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital
    • TANAKA Yoshihiro
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital
    • UCHIDA Takanori
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital
    • TAKANO Issei
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital
    • NAGAISHI Masaya
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital
    • KOWATA Kazuma
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital
    • HYODO Akio
    • Department of Neurosurgery, Dokkyo Medical University Koshigaya Hospital

抄録

The characteristics of intracerebral hemorrhage (ICH) accompanying chronic liver disease (CLD) were investigated in ICH patients hospitalized between 1998 and 2008 divided into the CLD group (55 ICHs in 49 patients) and the idiopathic group without CLD (668 ICHs in 648 patients). The CLD group included a subgroup with liver cirrhosis (LC). Age, sex, history of hypertension, Glasgow Coma Scale (GCS) score on admission, and hematoma locations were reviewed. Outcomes on discharge and causes of in-hospital death were also studied. Factors associated with life prognosis in CLD patients were investigated using uni- and multivariate analyses. History of hypertension and deep cerebral hemorrhage were less frequent in the LC subgroup compared to the idiopathic group. Distributions of GCS scores on admission were not significantly different, but incidence of in-hospital death was significantly higher in the CLD group than in the idiopathic group. LC was an independent prognostic factor for CLD patients, but hematoma enlargement was not. Death primarily due to ICH was less frequent in the CLD group than in the idiopathic group. In conclusion, hemostatic disorders seemed to be related to site of hemorrhage, but not to life prognosis in the CLD group. Prognosis was mainly worsened by non-neurological complications.<br>

収録刊行物

  • Neurologia medico-chirurgica = 神経外科

    Neurologia medico-chirurgica = 神経外科 52(4), 181-185, 2012-04-15

    一般社団法人 日本脳神経外科学会

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各種コード

  • NII論文ID(NAID)
    10030127710
  • NII書誌ID(NCID)
    AN00358613
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    04708105
  • データ提供元
    CJP書誌  J-STAGE 
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