Assessment of bactericidal effects of quaternary ammonium-based antibacterial monomers in combination with colloidal platinum nanoparticles
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- MA Sai
- Department of Prosthodontics, School of Stomatology, Fourth Military Medical University Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- IZUTANI Naomi
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- IMAZATO Satoshi
- Department of Biomaterials Science, Osaka University Graduate School of Dentistry
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- CHEN Ji-hua
- Department of Prosthodontics, School of Stomatology, Fourth Military Medical University
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- KIBA Wakako
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- YOSHIKAWA Ranna
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- TAKEDA Kahoru
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- KITAGAWA Haruaki
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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- EBISU Shigeyuki
- Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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Abstract
Pretreatment of dentin using colloidal platinum nanoparticles (CPtN) can enhance the bond strength of dentin adhesives. However, the combination of CPtN, which is negatively charged, with cationic monomer-containing adhesive may reduce the antibacterial activity of the original material. Thus, the purpose of this study was to assess the effect of CPtN on the bactericidal activity of two cationic antibacterial monomers, 12-methacryloyloxydodecylpyridinium bromide (MDPB) and methacryloxylethyl cetyl dimethyl ammonium chloride (DMAE-CB). The rapid killing effects of the two monomers against planktonic or attached Streptococcus mutans in the presence or absence of CPtN were examined by viable cell counts. The measurement of minimum inhibitory and bactericidal concentrations demonstrated that CPtN up to 2.5 mM has no antibacterial activity. In the absence of CPtN, rapid killing of both planktonic and attached Streptococcus mutans were achieved by the two cationic monomers. Combination with 0.1 mM CPtN did not reduce the bactericidal effects of the two monomers, indicating that CPtN may be used as a pretreatment with antibacterial adhesives.
Journal
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- Dental Materials Journal
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Dental Materials Journal 31 (1), 150-156, 2012
The Japanese Society for Dental Materials and Devices
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Details 詳細情報について
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- CRID
- 1390282679692070400
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- NII Article ID
- 10030128598
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- NII Book ID
- AA10443149
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- ISSN
- 18811361
- 02874547
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- Text Lang
- en
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed